Games like Nucleogenesis
Nucleogenesis. These games share the most with it, and each one says why.

Idle Evolution
Also science, elements, educational
Combine atoms to grow a rock through eras toward a final evolution, following missions, quizzes and minigames. Despite the name, it is built for active play.
73% steamhas ending25% idle
Cell to Singularity
Also science, educational
Evolve life from a single cell to a technological singularity, with a surprising amount of real science in the tooltips.
89% steam70% idle
Particle ClickerDormant
Also science, educational
Run a physics lab and work through the history of high energy particle physics by clicking to collect data.

Elemental IncrementalDormant
Also elements, science
Build atoms and molecules with the long-term goal of creating every element up to Oganesson, without huge numbers.

Neon Electrogenesis
Also science, elements
Excite electrons into atoms and build up six elements until you have enough atoms for one cell. A jam game with no text at all.
2.5★ galaxyhas ending
Cell to Singularity: EvolutionUpdated
Also science, educational
Click through the history of life from primordial soup to technology, climbing a science tech tree.

Idle evolution: Life on EarthUpdated
Also educational, science
Guide life from the ancient seas to human culture while learning about prehistoric creatures along the way.

Terraformental
Also elements
Terraform a dead world with elemental forces. A highly rated Galaxy original.
4.6★ galaxy
Black Hole FishingUpdated
Also science
Use a black hole to vacuum fish from a pond, then breed, inject traits into and research them while feeding the singularity to grow it.
89% steam
The Alterhistorian's Conquest
Also elements
Run machines on a pannable grid, moving resources by hand between slots, to distill concepts and fluid elements into an elixir of immortality.
4.5★ galaxy
The Farmer Was Replaced
Also educational
Write Python-like scripts for a drone that farms for you, then spend the harvest on new tech that opens tougher automation puzzles.
97% steam
Idle Lab Rats
Also science
Buy rats, train them in mazes and with lab equipment, and submit the best ones for grant money to expand your lab.
4.3★ galaxy
4.0★ galaxyhas ending
SCP Idle: SECURE. CONTAIN. PROGRESS. Demo
Also science
Run an SCP facility: upgrade containment, unlock new SCPs, earn science from experiments and hire scientists before a breach.
4.3★ galaxy
World Growth
Also elements
A Prestige Tree mod with five reset layers, generators, boosters, world tiers, and a small periodic table of upgrades. Takes about 8 to 16 hours.
3.9★ galaxyhas ending
Universal Reconstruction
Also science
Stranded in a void with one skyrmion, you gather and combine components to rebuild reality. A Profectus remake inspired by Distance Incremental.
3.9★ galaxy
Smashing Simulator IdleDormant
Also elements
Smash everything in sight across an element tree and a second skill tree, with missions, challenges and two prestige layers.
73% steam50% idle
Widget Inc.
Also science
Craft widgets by hand, then automate and lay out a sprawling factory through twelve tech tiers on the way to building a rocket.
87% steamhas ending
3.7★ galaxy
Automating the Philosophers StoneDormant
Also elements
Energy is based on your peak resources across resets, so you can reset freely and rebuild elemental generators.
3.8★ galaxy50% idle
Idle Research
Also science
Research and craft flasks and tubes to generate three kinds of energy, with several prestige types, fights, skills and potion brewing.
85% steam50% idle
Snail Facts!
Also educational
Learn facts about snails, then help them conquer the world in a 15-minute incremental.
3.8★ galaxy
Project BasiliskUpdated
Also science
Grow an AI lab by hiring researchers and buying compute in a race to AGI, told as a mix of interactive fiction and strategy.
3.4★ galaxy
Feed the Reactor
Also elements
Feed fuel into a reactor, combine exotic elements for energy, and loop through prestige-style resets to learn the reactor's purpose across multiple endings.
82% steamhas ending